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May 18 2018

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poolsofchrome:

The way isn’t always readily apparent

Reposted byIMS IMS
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catsigma:

Dismal

unavoidable-changes:

“PUT A NUMBER IN MY ASK”

— 1. Who was the last person you held hands with?
2. Are you outgoing or shy?
3. Who are you looking forward to seeing?
4. Are you easy to get along with?
5. If you were drunk would the person you like take care of you?
6. What kind of people are you attracted to?
7. Do you think you’ll be in a relationship two months from now?
8. Who from the opposite gender is on your mind?
9. Does talking about sex make you uncomfortable?
10. Who was the last person you had a deep conversation with?
11. What does the most recent text that you sent say?
12. What are your 5 favorite songs right now?
13. Do you like it when people play with your hair?
14. Do you believe in luck and miracles?
15. What good thing happened this summer?
16. Would you kiss the last person you kissed again?
17. Do you think there is life on other planets?
18. Do you still talk to your first crush?
19. Do you like bubble baths?
20. Do you like your neighbors?
21. What are you bad habits?
22. Where would you like to travel?
23. Do you have trust issues?
24. Favorite part of your daily routine?
25. What part of your body are you most uncomfortable with?
26. What do you do when you wake up?
27. Do you wish your skin was lighter or darker?
28. Who are you most comfortable around?
29. Have any of your ex’s told you they regret breaking up?
30. Do you ever want to get married?
31. If your hair long enough for a pony tail?
32. Which celebrities would you have a threesome with?
33. Spell your name with your chin.
34. Do you play sports? What sports?
35. Would you rather live without TV or music?
36. Have you ever liked someone and never told them?
37. What do you say during awkward silences?
38. Describe your dream girl/guy?
39. What are your favorite stores to shop in?
40. What do you want to do after high school?
41. Do you believe everyone deserves a second chance?
42. If your being extremely quiet what does it mean?
43. Do you smile at strangers?
44. Trip to outer space or bottom of the ocean?
45. What makes you get out of bed in the morning?
46. What are you paranoid about?
47. Have you ever been high?
48. Have you ever been drunk?
49. Have you done anything recently that you hope nobody finds out about?
50. What was the colour of the last hoodie you wore?
51. Ever wished you were someone else?
52. One thing you wish you could change about yourself?
53. Favourite makeup brand?
54. Favourite store?
55. Favourite blog?
56. Favourite colour?
57. Favourite food?
58. Last thing you ate?
59. First thing you ate this morning?
60. Ever won a competition? For what?
61. Been suspended/expelled? For what?
62. Been arrested? For what?
63. Ever been in love?
64. Tell us the story of your first kiss?
65. Are you hungry right now?
66. Do you like your tumblr friends more than your real friends?
67. Facebook or Twitter?
68. Twitter or Tumblr?
69. Are you watching tv right now?
70. Names of your bestfriends?
71. Craving something? What?
72. What colour are your towels?
72. How many pillows do you sleep with?
73. Do you sleep with stuffed animals?
74. How many stuffed animals do you think you have?
75. Favourite animal?
76. What colour is your underwear?
77. Chocolate or Vanilla?
78. Favourite ice cream flavour?
79. What colour shirt are you wearing?
80. What colour pants?
81. Favourite tv show?
82. Favourite movie?
83. Mean Girls or Mean Girls 2?
84. Mean Girls or 21 Jump Street?
85. Favourite character from Mean Girls?
86. Favourite character from Finding Nemo?
87. First person you talked to today?
88. Last person you talked to today?
89. Name a person you hate?
90. Name a person you love?
91. Is there anyone you want to punch in the face right now?
92. In a fight with someone?
93. How many sweatpants do you have?
94. How many sweaters/hoodies do you have?
95. Last movie you watched?
96. Favourite actress?
97. Favourite actor?
98. Do you tan a lot?
99. Have any pets?
100. How are you feeling?
101. Do you type fast?
102. Do you regret anything from your past?
103. Can you spell well?
104. Do you miss anyone from your past?
105. Ever been to a bonfire party?
106. Ever broken someone’s heart?
107. Have you ever been on a horse?
108. What should you be doing?
109. Is something irritating you right now?
110. Have you ever liked someone so much it hurt?
111. Do you have trust issues?
112. Who was the last person you cried in front of?
113. What was your childhood nickname?
114. Have you ever been out of your province/state?
115. Do you play the Wii?
116. Are you listening to music right now?
117. Do you like chicken noodle soup?
118. Do you like Chinese food?
119. Favourite book?
120. Are you afraid of the dark?
121. Are you mean?
122. Is cheating ever okay?
123. Can you keep white shoes clean?
124. Do you believe in love at first sight?
125. Do you believe in true love?
126. Are you currently bored?
127. What makes you happy?
128. Would you change your name?
129. What your zodiac sign?
130. Do you like subway?
131. Your bestfriend of the opposite sex likes you, what do you do?
132. Who’s the last person you had a deep conversation with?
133. Favourite lyrics right now?
134. Can you count to one million?
135. Dumbest lie you ever told?
136. Do you sleep with your doors open or closed?
137. How tall are you?
138. Curly or Straight hair?
139. Brunette or Blonde?
140. Summer or Winter?
141. Night or Day?
142. Favourite month?
143. Are you a vegetarian?
144. Dark, milk or white chocolate?
145. Tea or Coffee?
146. Was today a good day?
147. Mars or Snickers?
148. What’s your favourite quote?
149. Do you believe in ghosts?
150. Get the closest book next to you, open it to page 42, what’s the first line on that page? (via catscuddlingandyou)

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intindra:

Always a pleasure to do these studies, lobo-de-luna is the best.

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brokenheartsandflowerpots:

Just take it. There is no explanation.

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shiriosandmilk:

Preview of my piece for Ethereal @alteanlancezine :3

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maylovelies:

Jadzia rocked this outfit tbh,

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gradientgod:

Imma start charging people for hurting my feelings $3 a minute

burplesnurf2:

burplesnurf2:

burplesnurf2:

burplesnurf2:

the cha cha slide in full metal armor

“sliiide to the left”

*indescribably loud screeching of metal against asphalt*

“one hop this time”

*clonk*

“two hops this time”

*clonk clonk*

“everybody clap your hands!”

*clankclankclankclankclank*

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fuckyeahanarchistposters:

Harry Patch: The stirring words of Britain’s ‘last fighting Tommy’

“WAR isn’t worth one life,” Harry Patch - the man nicknamed “the last fighting Tommy” - said before his death on July 25, 2009.

Mr Patch, who was the last British First World War soldier to pass away, became a symbol of dignity and unswerving honesty about the horrors of the trenches.

The veteran, of Combe Down, a small village near Bath, was born on 17 June, 1898 - while Queen Victoria was still on the throne.

He was conscripted into the Duke of Cornwall’s Light Infantry in 1917 and trained as a machine gunner - having left school at the age of 13 to train as a plumber.

Despite not breaking his silence about the Great War until after his 100th birthday, Mr Patch became famous for the unerring humanism of his words.

In recorded excerpts of his memoirs, he said: “I had no inclination to fight anybody. I mean why should I go out and kill somebody who I never knew? For what reason?”

Mr Patch found himself en route to Reims on his 19th birthday and installed in the trenches in July, 1917.

He arrived in time to witness the Third Battle of Ypres, also known as the mud-soaked offensive, Passchendale.

His brother had been injured in Mons while serving with the Royal Engineers and Mr Patch said he knew he did not want to take to the deep trenches, surrounded by filth and exploding shells.

He said: “I think every man who went on the front line at some time or another was scared. And if any man tells you he wasn’t scared then he’s a damn liar.

“When it came to the point where we went into action I was scared stiff because I thought the first time I go over the top - you don’t know how much longer you are going to live.”

Questioning the “war to end all wars”, he said before his death: “It wasn’t worth it. No war is worth it. No war is worth the loss of a couple of lives let alone thousands.”

After the conflict he returned to plumbing and raised his family in the West Country. When he died in his sleep at a nursing home in Wells, Somerset he was Britain’s oldest man.

A Single Pale Rose (2018)

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firelightmystic:

So what, none of you punks were gonna tell me Don Cheadle out here all kingly dapper af looking like some kind of aristocratic bamf? WITH A SWORD?? I had to stroll up on this all unexpected???

I was looking for suit pictures, I wasn’t out here trying to thirst after the man, but here we are now, and I hope all of you are happy.

shadowphoenixrider:

botanyshitposts:

botanyshitposts:

so uhhhhhh i know this is a plant blog but realtalk lads im a little freaked out by that wild ass new organ discovered in our bodies according to a paper published literally yesterday am i right my lads, my bois, lmao hhaha

(as of 3/28/2018, paper was published in the reputable international research journal “Nature” on 3/27/2018, publication here, study was started in 2013) ok so like uhhh this is my rough translation of the paper they published using my current level of biological knowledge, if anyone else has a more in depth understanding with human anatomy things and would like to add on with anything i might have missed feel free to add but this is my takeaway: 

-scientists were looking at some stuff in the inside of a bile duct they were studying in a live patient (this will be important later) using a laser that lets them see the cells in real time. they injected some stuff into the duct and saw the spaces inbetween the cells fill up with fluid in strange, tube-like structures that didn’t correspond with what they expected to be there, so they sectioned and froze them to study them closer; they realized that upon closer inspection, the fluid-filled places were VERY small collagen tubes forming a complex matrix of bundles surrounded by a weird cell covering that seemed to connect them to one another. they called this the Interstitium. 

-they sectioned some more places where squeezy things might happen, like the inner linings of the bladder, lungs, lymph nodes, and the soft tissue enclosing our muscles, filled them with the same indicator, and hyper froze them like they did to the first sample and found the same weird matrix of fluid-filled tubing:

image

they concluded from what they found from this that: 

1. our previous thought of the space inbetween the cells in these parts of the body, which we thought were just kinda like, there or whatever doing nothing (a series of spaces that were already called the Interstitium that were largely ignored), are actually full of complex tubing running through a ton of very important parts of your body

2. when the structures they’re chilling around (like your bladder and bowel) contract, the fluid moves around all weird

3. the reason this wasn’t discovered before is because when the tubes are squished too hard- like when scientists are cutting into them- they have a tendency to collapse really easily, especially when being treated with chemicals for microscope use, giving the impression of the kind of tissues that we’ve traditionally seen in specimens and thought of being in these sensitive areas (closely compact and dense cell mats). it turns out that in living people, these tubes run between the cells carrying fluid; the scientists were able to see this initially in live patients using the above mentioned laser technology, and then took live biopsies by quickly freezing the cells in place before removal to prevent their collapse.

4. yes, these can move cancer cells around, which is HUGE seeing as they seem to enclose a LOT of important and delicate muscles in our bodies in one giant, complex system. when they looked at it in cancer patients, the tumors they found seemed to kind of be….leaking….into them…..because the tumors were putting pressure on the fluid tubes….which easily collapse…..and move things that fall into the fluid around….

5. the scientists also explored things like hernias and colon damage in relation to these, but unfortunately this is where my translation powers run out as non-plant-related terminology starts being used lmao im so sorry im like this

tl;dr: the membranes that surround some really important parts of squishy things like our stomach, bowels, colon, lungs, muscles, etc are full of very delicate and complex tubing that runs in a weirdly complex system to other important squishy things throughout our bodies and looks like a weird organ that we didn’t know was there before (or like, we knew about it, we just didn’t know it was so…connected and uh…organy). also it seems to have an impact on the spread of cancer throughout these regions

here’s the paper again if you want to have a read and see pics of the tubing itself and draw more in depth conclusions from it lmao 

Graduate of Biomedical Science here; this paper is pretty much understandable to me.

You’ve picked out the main stuff, but here’s some things I think is very interesting:

  • The discovery of these spaces dramatically expands the lymphatic system. Basically, this is how the lymph nodes are connected to the rest of the body. Before it was kinda like ‘yeah here are the lymph nodes, and the lymph fluid kinda goes to the somehow? idk’. But now we have a whole system. It’s like discovering the entire circulatory system when before you only had the heart to work with.
  • This is super important for cancers and detecting when a cancer has spread (metastasised, in the lingo). They talk about the spread of cancers into the deeper tissues (such as stomach cancers invading their submucosal tissue and skin cancers pentrating deeper into the dermis layers), but what is most important is that they detected the cancers spreading into the interstitial spaces before there was anything to detect within the lymph nodes. This is super important, as usually lymph node biopsies are done to detect if a cancer is spreading; this is before that very stage. This is literally catching cancers in the act of spreading before they’ve hit another organ this is fucking incredible.
  • It’s providing an explanation for oedema (or edema, for my US followers), which is the build-up of fluid in certain areas of the body (usually the lower limbs, but it can be anywhere). For so long it’s been like ‘I guess there’s something wrong with your blood vessels??’ but like the lymphatic system, we’ve now got another explanation. ‘Ah, okay, there’s something going down in your interstitial fluid!’ A more effective diagnosis and treatment could be made, Bam! Enrich more people’s lives.
  • They may play a role in how scar formation works. Some scar tissue can get a bit crazy and grow too much, meaning it needs to be cut away as it hinders movement or it just fucking painful. Perhaps the interstitial tubing/fluid plays a role in this, considering collagen is used in scar tissue, and these spaces are full of it.
  • There’s clearly communication between these spaces and the digestive system, as they found tattoo pigment from the intestines in these spaces. Tattooing in the intestine is done to mark lesions for removal or observation later on, so the fact this pigment is actively moving out of the digestive system and else means it could play a role in disease we don’t know much about, like inflammatory bowel conditions.

Basically, THIS IS FUCKING HUGE AND COULD POTENTIALLY CHANGE THE GAME IN A BIG WAY.

Thank you OP for sharing this, I haven’t nerded out and been so fascinated by a study in a long time.

ALSO GOOD ON YOU NATURE FOR MAKING THE FULL ARTICLE FREE. HONOUR ON YOU AND YOUR COWS.

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3lunch:

Champion

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3lunch:

Champion

daysoffuturepast:

Muslims fasting and taking exams at the same time during Ramadan are braver than any US marine.

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bevsi:

Aluna & Sylvie hairstyles

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kaechristen-art:

-  I grew up watching this show as a teen, and I am getting so emotional over it!

 Growing up makes me feel a bit nostalgic :’)

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